Smiley becomes reacquainted with his former flame Cassandra, a gospel/blues singer, whom is the suspect in the murder of a record company mogul that Remy is investigating. When evidence clears Cassandra, Remy puts his focus on other suspects whom include the doorman LaRue as well as a Cassandra's sleazy manager, Dominick, in which Janine decides to go undercover to look for evidence against him.
Remy, Janine, C.D. and the team investigate the shooting spree at a local restaurant where the owner apparently died from sheer fright. But when Remy learns that the victim was in fact poisoned, he sets out to find the culprit. This leads him from the shooting culprit, Angela, whose father was in competition with the murder victim, which leads to a shady produce entrepreneur, whom was in feud with the victim.
Remy and Janine team up with a shady, alcoholic Russian agent whom is in New Orleans looking for a missing challis which was stolen from a local Russian Orthodox church resulting in the murder of the caretaker. But there's more complications when an equally shady female American Interpool agent, named Mariel Rigg, also arrives looking for the challis and has her own agenda.
The Big Easy television series was inspired by the film of the same name from 1987. The show premiered on the USA Cable Network August 11, 1996. Tony Crane played New Orleans police lieutenant/detective Remy McSwain, Susan Walters played state district attorney Anne Osbourne and Barry Corbin played police chief C.D. LeBlanc. Daniel Petrie Jr. was the executive producer of the series. 35 episodes were broadcast over two seasons. The series takes place in New Orleans, Louisiana and was shot on location.