The team searches for his serial killer named Carol Eisenberg who along with her husband killed five girls. Now she has escaped from prison. Also Jess warns Antonio that someone may harm him. Her vision turns out to be correct when Antonio realizes he's being stalked by a dead man.
Nicole gets to know her mom and tries to get to know her better. They also try to find a missing Department of Justice agent and try to find out why and who blew the cover of the DOJ agent.
This case may be the toughest one the team has had yet. When the inventor of Easy Abs is nowhere to be found the team finds a ransom note and then another ransom note. What has the team confused is the two different amounts on both ran some notes.
Nicole and Jess travel to Budapest Hungry to track down a missing bridegroom.
In what may be the most bizarre case yet for the FBI squad, the team must find missing twin girls in order to figure out who killed their parents and why! Jess' visions suggest that the girls are separated but both lost in the wilderness.
Antonio, Jess and Colin give up their vacation time to help Nicole investigate the disappearance of her nephew.
The agents search for a wealthy businessman who disappeared from his hotel. They try to get the truth out of his girlfriend, who discovered him missing in the middle of the night. When Pollack's team is ordered off the case by his boss, he risks his job to continue working on it. Meanwhile, Pollack tries to reconcile with his wife.
Jess has a vision that leads her and Nicole to discover a 10-year-old skeleton. When the body is identified, Pollack orders them off the case. Jess and Nicole continue to work on the case while trying to keep their work away from Pollack and trying to figure out why he's so insistent that they can't work on it. Meanwhile, Pollack's wife kicks him out.
The team shifts into high gear to find an abducted newborn while dealing with a traumatized mother. Jess' visions are challenged due to the infant's lack of life experiences. Nicole and Antonio continue to try and hide their relationship from Jess, who is starting to suspect something.
Jess Mastriani was a normal person who only wanted to take over her parents' restaurant in Indiana. But that changed when she was hit by lightning. After that she began seeing visions of missing people. Jess decides to use her newfound ability to be a consultant to the FBI, helping locate missing individuals. Eventually, she is hired by the bureau full-time and trained to become an agent, but her by-the-book nature sometimes clashes with the personality of her partner. Jess and her colleagues work out of the FBI's Washington, D.C., office.