McKenna's friend Heather moved away and the Care Bears and the Thunder Whales help her feel better about Heather's absence.
McKenna and the other Care Bears help Grumpy get over his fear of riding a bicycle.
After several mishaps while preparing for a race, Oopsy believes himself to be bad luck until he receives a clover from Good Luck.
McKenna is taught about the joys of giving; Grizzle gives the Care Bears a gift and invites them to his lair for a larger gift; one he intends to use to trap them.
Grizzle has created another device to steal the Care Bears belly badges and uses it on Funshine.
Bumpity and Tweazle try to create winter conditions to allow the Care Bears and McKenna to enjoy winter activities, but they accidentally create No Snow, an opposite form of snow that can invert one's attitude (positive to negative and vice versa).
Bedtime allows Funshine, Tenderheart, Oopsy to accomanpy him on a typical work shift, which includes helping Hugs and Tugs get to sleep and keep everyones' dreams running smoothly.
Harmony has the most lovely voice in Care-a-Lot, but when True Heart plans a big concert for Harmony to sing, all the extra attention begins to go to Harmony's head. Now True Heart must deal with an unruly and ungrateful friend, and hope to correct the misdeeds of the monster she created.
When Grizzle loses Mr. Beaks, he leaps to the worst conclusion—that his pal has been stolen by the Care Bears. The Care Bears don't agree with his conclusion, but agree to help anyway. Funshine and Love-a-Lot decide to play detective and are soon giving everyone in Care-a-Lot the third degree. Meanwhile, Oopsy and Grumpy work on their own plan to help Grizzle.
Grumpy finds a special Bumbleberry bush and refuses to share.
True Heart trips and is teased.
Care Bears: Adventures in Care-a-lot is an animated television series by SD Entertainment, Cookie Jar Entertainment and Shari Lewis Enterprises that premiered on CBS's KEWLopolis line-up from September 15, 2007 to December 6, 2008, and is designed to be an immediate follow up to the movie Care Bears: Oopsy Does It!. It was the third Care Bears television series made and was produced by Sabella Dern Entertainment, the same company that made Care Bears: Oopsy Does It!. It features songs with music by Andy Street and lyrics by Judy Rothman. Along with the other shows in the KEWLopolis block, this series fulfills the federal "E/I" requirements.