After discovering a swear word scrolled on Andy's lunchbox, Bob decides that enough is enough and he forms a vigilante group that will help him fight against the evils of society, but will Bob still manage to perform the tasks God has in store for him, or will all the exposure get to Bob’s head?
God's girlfriend walks back into his life after leaving him because he was always so busy; Bob attempts to help him win her heart back, but will God be capable of watching over the world and courting his girlfriend without complications?
God is disgusted with how much sex is shown on television and he decides to get Bob to go to Hollywood to get them to limit the amount of sex that can be on television. Bob is reluctant, but he soon comes to his senses when he realizes Andy has seen something he shouldn't, but will he be capable of opposing one of the most powerful people in the world alone?
God is feeling lonely because he doesn't really have much of a social life (due to being God) so he decides to try to live life as a human being; he gets a job as an auto worker at the plant where Bob works.
God wants Bob to do something about his adulterous neighbor, which God is frustrated about because it's definitely a sin. Bob reluctantly accepts the assignment, but soon realizes that things are going to go much different than he expected.
God strikes a wager with the Devil: if just one person can convince him that the world is worth saving, he'll spare humanity from destruction, if not, God will scrap all of creation and start over. The Devil is allowed to choose the candidate, and true to form, he picks the least likely person to determine the fate of the world--self-centered, slow-witted Detroit autoworker Bob Alman, an icon of mediocrity. Reluctantly, Bob accepts God's challenge, and has to live a decent life with no hints from God and constant temptation from the Devil. Caught between the forces of divinity and deviance, with the weight of the world on his shoulders, there's nothing left to do but laugh.