Angela is haunted by the apparent ghost of a pilot who disappeared two years ago.
The team uncovers a Sentient plot to use elementary school students in the creation of a Doomsday weapon.
When Taggart wakes up in a hospital with Paige beside him, he begins to believe that the destruction of the world may have been a dream. What he doesn't know is that it is all a ruse by Dr. Bertran, who is trying to stall his activities long enough to download information from his brain.
With the still-grieving Chuck having taken off on a road trip, the rest of the crew have to deal with the synthetic that Kurt has created.
The O-5 team is approached by "Harry Mudd" -- a Sentient in a Synthetic body. He warns them of the imminent destruction of the world by an insane Sentient and reminds them about what's important in life.
The residents of a small town and a select group of scientists (including Mendel) are brainwashed into believing "The Lord" has specially chosen them to construct a passageway designed to bring "Him" to Earth. Taggart and Neil must reach Mendel, before it's too late.
A mysterious being, who is not bound by time, notes that the Odyssey crew have jumped out of their proper time and comes to investigate them. It probes their minds and forces them to re-visit the personal choices they made in the most important moments of their past lives.
Odyssey 5 is a Canadian science fiction series that first ran in 2002 on Showtime in the United States and on Space in Canada. Odyssey 5 is the brainchild of Manny Coto, who served as a script-writer and executive producer during the series run. Through his website and in interviews, Coto has expressed his interest in returning to the series at some point, either continuing it or giving it a conclusion.