Kirk Manlord, the host of a sleazy reality show Bonafide Heroes about universe's heroes, does a piece on Duck Dodgers. The crew follows Duck 24/7 and interviews his enemies and friends. Dodgers decides to use this opportunity to promote himself.
I.Q. Hi joins Dodgers and the Cadet for his annual ride along misadventure. Dodgers and the Cadet gradually grow tired of I.Q. Hi tagging along and they ask the Martians to fake an attack, so I.Q. Hi can save the day and leave. Unfortunately, the Martians plan to attack for real.
The Martians create a weapon to drain energy from Earth's music and use its atomic power to destroy the Earth. Dodgers unfreezes Megadeth star, Dave Mustaine, to play enough heavy metal to overload the device.
When a crime family corners the galaxy's chewing gum market, Dodgers and the Cadet recruit rival gangsters to fight crime with crime.
A lightning-fast burglar eludes the Galactic Protectorate, forcing Dodgers and Cadet to track down an imposing Kung Fu master for assistance.
A psychic supervillain named Manobrain, steals top secret codes and hides them in Dodgers' brain. I.Q. Hi, Cadet, Manobrain, and embodiments of Dodgers' personality explore his mind in their quest to find them.
When Hungortus the Eater of Worlds heads toward the solar system for his next meal, Dodgers and the Martians hire lawyers to convince him of which planet to eat: Earth or Mars.
A criminal gambling kingpin hires a gang of bounty hunters to kill Dodgers, but his plan goes downhill when one of the bounty hunters quits and offers to help Dodgers.
While on a diplomatic mission to an aquatic planet, Dodgers instigates war between the dolphin and shark people. Dodgers and Cadet are drafted to fight on opposing sides, but must find a way to bring about peace.
The Martian Queen hires the highly unusual assassins Hubie and Bert, who trick Dodgers and Cadet into thinking the other is out to kill them.
After being injured, Dodgers receives cyborganic parts, which give him super powers. Meanwhile, the Martian Queen and X-2 kidnap other cyborg people from Earth to steal their technology, using the dubious help of Dr. Maniac.
When the Cadet quits the Protectorate to become a big corporate CEO, Dodgers decides to get him back by sabotaging his company with the help of his new Cadet, Egghead Jr.
Dodgers and the Cadet team up with officer Paprika Solo on Groovica to discover the location of the galaxy's missing supply of diamonds.
Dodgers invites people to a party to celebrate his new Lifomatica, a system designed to make life easier. That is, until Lifomatica goes insane and traps the guests inside the ship.
Dodgers and Star Johnson go against each other to win the "Captain of the Year" award and the heart of a female Lieutenant.
I.Q. Hi builds a detoxification machine and uses it on Dodgers as a test subject. The machine rids Dodgers of anything impure and turns him into the perfect duck. But Dodgers' friends and enemies quickly learn they like the old Dodgers better.
Dodgers, Cadet, Dr. I.Q. Hi, The Martian Queen, Martian Commander X-2 and a random centurion fall for an Internet scam. A random stranger forces them to fight for their lives.
Dodgers and Cadet go undercover in one of earth's high schools in order to stop a martian spy from sending earth's teenagers into lunatics.
The Cadet and the Centurions go on separate vacations away from their bosses.