Aptom manages to infiltrate into Relic's Point and finally takes his revenge on Zector, Guster and Dezerb. Chased by Alkampfer, Guyot escapes to the lower levels, while Sho suggest that the whole group finds shelter inside the Crypt. Finally facing each other, Alkampfer and Guyot start their fight, and the latter unleashes his most powerful attack.
Guyot sends a group of chosen Zoanoids, the Lost Numbers, against Sho to keep him busy and kidnap his father, Tetsuro and Mizuki at the same time. Guyver I defeats his three enemies, but Guyot's plan works: Sho must hurry to save his closest friends and his father, now with the help of the mysterious guy that previously helped him.
Sho's reapperance shocks Tetsuro that immediately tries to figure out how his friend managed to come back to life. Suddenly, self destruction mode is activated inside Cronos building, forcing everyone, included Guyot, to run away. Before leaving together with Tetsuro, Sho has a final encounter with Lisker in his Guyver II form.
Mizuki stays at the hospital after suffering a trauma caused by the kidnapping attempt, and Sho decides to fight Cronos alone so his loved ones won't be in danger because of him. Meanwhile, Guyot sends against Guyver a new experimental Zoanoid, originated from Genzo Makishima. A deadly fight begins, with a surprising ending.
Sho and Tetsuro try to deal with the events that lately happened in their life. Meanwhile, at Cronos, Genzo is visited by inspector Lisker, who tells him that the headquarters are disappointed by his recent failures. Nevertheless, Genzo sends one of his best men to recollect Sho's unit, but with no luck.
Guyver: The Bioboosted Armor is a Japanese anime series based on the long-running manga series, Bio Booster Armor Guyver, written by Yoshiki Takaya, adapting chapters 1 - 59 of the manga. The production was in association with ADV Films and Kadokawa Shoten. The series first episode aired in Japan on August 6, 2005 and the last episode aired on February 18, 2006. The series aired in North America on December 20, 2010, on the FUNimation Channel.