Mike and KITT must find a stolen serum which will result in the recipients maximum physicality when used, before it lands into the wrong hands. Meanwhile, Sarah's new duties have her overwhelmed as she quickly learns what it will take to re-institute the Foundation for Law and Government.
During his "decompression" time, Mike visits an old hangout---Sonny's Bar---and helps the new proprietress restore the joint to its original glory. But Mike must square off against a mysterious someone who wants the bar sold, and that person may resort to arson to fulfill that desire.
Mike becomes a hostage in a bank robbery when he becomes entangled with one of the robbers. As he tries to stop the thieves his efforts are hampered by the twists, turns and being uncertain of what the motives for the robbery was all about.
Michael and KITT continue on a mission to rescue an ambassador and foil the terrorists holding him. The quest becomes even more dangerous when a bomb is placed inside of KITT, set to explode when the car reaches a certain speed. Meanwhile, Sarah receives shocking information regarding her father.
A deranged terrorist has kidnapped a foreign ambassador, sending Michael and KITT out to the rescue. Elsewhere, a damaged robot has Dr. Graiman and Sarah teaming up to repair it.
The world is in jeopardy when a devastating computer virus is released. With Kitt infected by the bug, it may mean the ultimate stall out. Elsewhere, Mike becomes jealous when Sarah and her ex-beau reconnect.
Billy tags along with Mike as he heads to Vegas on a mission to stop a money laundering ring, and Billy has his eye on finding romance along the way. Meanwhile, The KITT cave is assessed and also locks horns with an old nemesis, Dr. Graiman.
Knight Industries tracks down a Bonnie and Clyde-esque couple and find that their true identites will affect a congressional race. Meanwhile, Mike and KITT must find a way to save Agent Rivai.
When a tech is murdered inside of Knight Industries, the team must track down the person that infiltrated headquarters before they strike again. Meanwhile, Mike and Sarah find themselves stuck together during a storm.
Mike goes undercover as an AWOL Marine in order to find a rogue military officer. A beautiful undercover agent pairs up with Mike to help him solve the crime. Back at the SSC, Billy undergoes training with the help of Zoe.
A lethally poisoned Mike must fake the assassination of a tech bigwig in order to obtain the antidote. Meanwhile, hallucinations and the reemergence of an enigmatic woman shine light on Mike's hazy past.
Mike and Zoe go undercover in Baja as a honeymooning surfer couple in order to stop terrorist weapons from getting into the states. Sarah and Billy are brought into the mix and they quickly find the mission taking an unusual turn.
Mike enlists an old Army buddy to help take down a drag racing gang which is also in the business of arms smuggling overseas. Sarah joins Mike and KITT despite her father's disapproval.
On the heels of NBC's hit movie, the iconic 1980s television classic comes roaring back to life as a reinvented, updated and super-charged action series showcasing the new KITT (Knight Industries Three Thousand). Absolutely the coolest car ever created, KITT is equipped with an "AI" (artificial intelligence) that is capable of hacking almost any system. Its weapons systems match that of a jet fighter, and its body is capable of actually transforming into other vehicles and using sophisticated holographic imagery to elude villains.